Antibiotics Cipro

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Cipro

Active Ingredients:

ciprofloxacin

The commercial name of the medication may differ from the brand one. Generic Cipro manufactured by Cadila Pharmaceuticals is available under commercial name Ciprodac.

Action mechanism and therapeutic effect of the medication:
Broad-spectrum antibiotic, belongs to fluoroquinolones II generation. Breaks the biosynthesis of DNA, growth and replication of bacteria; causes significant morphological changes (affecting cell walls and membranes) and rapid cell death. Affects microorganisms in the period of growth and rest. Most active against Gram-negative bacteria, in a lesser degree affects anaerobes.

Medical indications:
For systemic use: bacterial infections caused by susceptible organisms

infections in otolaryngology (otitis media, frontal sinusitis, sinusitis, mastoiditis, tonsillitis, pharyngitis)
lower respiratory infections (bronchitis and acute exacerbation of chronic pneumonia, bronchiectasis, cystic fibrosis)
infections of pelvic organs (cystitis, pyelonephritis, prostatitis, adnexitis, salpingitis, oophoritis, endometritis, tubular abscess, pelvioperitonit)
infections of skin and soft tissue (infected ulcers, wounds, burns, abscess, phlegmon)
infections of bones and joints (osteomyelitis, septic arthritis)
sexually transmitted diseases (gonorrhea, chancroid, chlamydia)
infections of the abdominal cavity (bacterial infections of the gastrointestinal tract, gallbladder and biliary tract, intraperitoneal abscess, peritonitis, salmonellosis, typhoid fever, campylobacteriosis, yersiniosis, shigellosis, cholera)
bacteremia, septicemia, severe infections on the background of immunodeficiency and neutropenia, prevention of infections during surgery

In ophthalmology: infectious and inflammatory eye diseases

acute and subacute conjunctivitis
blepharitis, blepharoconjunctivitis
keratitis, keratoconjunctivitis, bacterial corneal ulcer
chronic dacryocystitis, infections of the eye after trauma, pre-and post-surgical prevention of infectious complications in eye surgery

In ENT: otitis externa, treatment of post-surgical infectious complications

Cipro contradictions, precautions and warnings:

hypersensitivity (including to other fluoroquinolones)
glucose-6-phosphate dehydrogenase deficit
pediatric and adolescent patients
pregnancy, breastfeeding
in ophthalmology: viral keratitis, pediatric patients
with caution: severe cerebral arteriosclerosis, cerebral circulation disorders, mental illnesses, epilepsy, epileptic syndrome, renal and / or liver insufficiency

Cipro side effects: As with any other drug, side effects can occur with ciprofloxacin. However, it does not mean that everyone who takes the medicine will experience these adverse effects. In most cases the preparation is well tolerated. Cipro may cause the following side effects:

digestive system: nausea, vomiting, appetite disorder, diarrhea, constipation, pseudomembranous colitis, epigastric and abdominal pain, abdominal discomfort, hiccups, ulcers, dryness and soreness of the oral mucosa, flatulence, gastrointestinal bleeding, pancreatitis, cholestatic jaundice , hepatitis, necrosis of liver cells
nervous system and sense organs: headache, dizziness, excitement, anxiety, insomnia, nightmares, confusion, depression, phobias, fatigue, blurred vision, taste perversion, tinnitus, transient hearing loss, mood lability, gait disturbance, increased intracranial pressure, paresthesia, sweating, ataxia, tremors, convulsions, toxic psychosis, paranoia, hallucinations, headache
cardiovascular system and blood (hematopoiesis, hemostasis): blood pressure decrease, cardiovascular collapse, arrhythmia, cerebral thrombosis, paroxysmal tachycardia, leukopenia, leukocytosis, anemia, thrombocytopenia, thrombocytosis, prothrombin level changes
respiratory system: pulmonary embolism, dyspnea, respiratory distress, bronchospasm
locomotor system: arthralgia, myalgia, tenosynovitis
urogenital system: repeated urination, crystalluria, hematuria, cylindruria, polyuria, proteinuria, acidosis, urinary retention, hemorrhagic cystitis, nephritis, vaginitis, gynecomastia
allergic reactions: rash, petechiae, blisters, papules, cutaneous vasculitis, Stevens-Johnson syndrome, Lyell syndrome, exudative erythema multiforme, exfoliative dermatitis, itchy skin, swelling of the lips, face, neck, conjunctiva, limbs, angioedema, urticaria, anaphylactic shock
other: hyperpigmentation, eosinophilia, fever, photosensitivity, increase of level of liver transaminases, alkaline phosphatase, creatinine, urea, serum triglycerides, glucose, potassium, bilirubin; dysbiosis, candidiasis

If any side effects occur during the treatment make sure to consult your health care provider immediately. If you are unsure about anything related to ciprofloxacin, please talk to your doctor or pharmacist.

Drug interaction:
Cipro can potentially interact with the following groups of drugs:

other antibiotics
antacids
gastroprotective agents
drugs containing Bi, Fe, Zn
multivitamins
HIV-infection agents
anti-gout medicines
caffeine
bronchodilatators
oral anticoagulants
immunosuppressants
NSAID's

It is possible that all drug interactions are not presented above. For this reason, we recommend you to talk with your health care provide about drug interactions with ciprofloxacin which may apply to you.

Additional information for the patients:
The preparation should be taken according to your doctor's recommendations. Never take the drug for conditions which are not presented in the the drug's leaflet. Try to keep the medicine out of the reach of children.