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Antiplatelet Agents
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Antiplatelet agents are medications which inhibit the platelets and erythrocytes aggregation, lower their ability to agglutination and adhesion to endothelium of the blood vessels. By lowering the superficial tension of the erythrocytes aggregation, they lighten their deformation during flow throughout the capillaries. Some of the anti-platelet agents are able not only to prevent platelets aggregation but also cause disaggregation of the already aggregative blood plates.
Antiplatelets agents are used for prevention the formation of the blood clots, in thrombophlebitis, thrombosis of the retina vessels, disorders of the brain circulation as well as prophylaxis of tromboembolic episode in coronary heart disease.
Antiplatelet agent include medicines from different pharmacological groups. These groups include
- Organic nitrates
- Antagonists of calcium ions
- Purine derivates
- Antihistamine drugs
The examples of antiplatelet agent include clopidogrel (Plavix), acetylsalicylic acid (Aspirin), ticlopidine (Ticlid ®), dipyridamole (Persantine).
All of the antiplatelet agents including and aspirin can cause serious and even fatal adverse reactions when are not taken exactly as prescribed by a doctor. Prior to taking any antiplatelets agents make sure to discuss with your doctor the medicines and dosage regimen for your conditions.
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