Cholesterol Zocor

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Zocor

Active Ingredients:

simvastatin

The commercial name of the medication may differ from the brand one. Generic Zocor manufactured by Okasa is available under commercial name Simlip.

Action mechanism and therapeutic effect of the medication:
Zocor contains the active ingredient Simvastatin which is obtained synthetically from the fermentation product Aspergillus terreus. Simvastatin is metabolized into its active form in the organism where it blocks the enzyme called HMG-CoA reductase. This enzyme is responsible for the production and synthesis of cholesterol by the liver cells. Zocor lowers the amount of cholesterol in the blood, LDL, VLDL, triglycerides.

Medical indications: Zocor is approved to treat the following conditions:

Hypercholesterolemia
High triglycerides blood levels
Reducing the risk of heart attacks, strokes
Reducing the progression of atherosclerosis

Zocor contraindications, precautions and warnings:
Zocor should not be taken in the following conditions:

Hypersensitivity to any of the drug ingredients
Pregnancy
Breastfeeding
Liver diseases
Increased activity of transamines

Zocor should be used with caution in patients who abuse alcohol

Zocor side effects: As with any other drug, side effects can occur with Zocor. However, it does not mean that everyone who takes the medicine will experience these adverse effects. In most cases the preparation is well tolerated. Zocor may cause the following side effects:

Digestive system: stomach pain, constipation, meteorism, nausea, dyspepsia, vomiting, jaundice, increased activity of transaminases
CNS: headache, dizziness, paresthesia, peripheral neuropathy.
Allergic reactions: Quinke's edema, vasculitis, thrombocytopenia, eosinophilia, increased BSR (blood sedimentation rate), hives, photosensibilization, fever, hyperemia of the skin, labored breathing.
Other: asthenia, anemia, increased CPK (creatine phosphokinas), in rare cases myopathy.

If any side effects occur during the treatment make sure to consult your health care provider immediately. If you are unsure about anything related to Zocor, please talk to your doctor or pharmacist.

Drug interaction: Zocor can potentially interact with the following groups of drugs:

Blood thinners
Other anti-cholesterol preparations
Anti-fungals
Niacin preparations
AIDS preparations
Antidepressants
Calcium channel blockers
Cardiac glycosides
Grapefruit products
Immunosupressors

It is possible that all drug interactions are not presented above. For this reason, we recommend you to talk with your health care provide about drug interactions with Zocor which may apply to you.

Additional information for the patients:
The preparation should be taken according to your doctor's recommendations. Never take the drug for conditions which are not presented in the the drug's leaflet. Try to keep the medicine out of the reach of children.